What are the Advantages of High Pressure Homogenization for Nanoparticles?

by | Apr 20, 2022 | Pump Manufacturers

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Nanoparticle research is of high interest and widespread, especially in the scientific community. Scientists continue to probe further because it has uses in protein detection, gene delivery, drug delivery system, tissue engineering and also fluorescent biological labels. Even though nanoparticle preparation can be achieved through varied methods, high pressure homogenization nanoparticles are common and the benefits are given below.

Options of hot and cold homogenization – High pressure homogenization can be achieved by making use of cold or hot temperatures. Hot homogenization utilises heat that is above the lipid melting point so that an aqueous phase can be achieved. But, in drug delivery, hot homogenization has some drawbacks and these can be overcome with the help of cold homogenization. Researchers can choose the right homogenization method according to the circumstance.

• Results can be optimised by customisable forces

High pressure ho ogenizers used for high pressure homogenization nanoparticles combine mechanical and pressure forces to attain a consistent and uniform product. Mechanical forces may include shear, impact, turbulence, process intensity and cavitation. Premium quality homogenizers provide the option of easily adjusting these forces so that results can be optimised. This is key to getting a functional nanoparticle.

• The particle sizes are smaller compared to other equipment

A significant amount of pressure is exerted on the product, along with the actions of mechanical forces and this makes high pressure homogenizers different from other mixing equipment. The forces enable the synthesis of smaller particle sizes, which results in increased nanoparticle surface area and also bioavailability. These factors are important, especially for drug delivery systems.

So, these are a few benefits of high pressure homogenization nanoparticles. You can speak to an expert to find out more about high pressure homogenizers and their use.